The Matsumoto City Museum of Art's greatest feature is the breadth of its collection. It is one of the leading art museums in Japan, with collections of various genres of art, including Japanese paintings, Western paintings, sculptures, crafts, and prints.

The Matsumoto City Museum of Art engages in a variety of cultural activities that go beyond being an art museum. Various events such as concerts, theater performances, and movie screenings are held here, making it a hub for local culture.